Endocrine and Psychiatry Center logo

Diabetes type 1 and 2 medicatons

Mar 08, 2023
misc image
We go over type 1 and type 2 diabetes medicatons

Diabetes is a chronic health condition that affects millions of people worldwide, including those in the United States. One of the primary treatments for diabetes is medication, which can help regulate blood sugar levels and prevent complications. In this article, we will discuss the various types of diabetes medications available and how they work.

Type 1 and Type 2 Diabetes

There are two main types of diabetes: type 1 and type 2. Type 1 diabetes occurs when the body does not produce enough insulin, while type 2 diabetes occurs when the body becomes resistant to insulin or doesn't produce enough insulin. Both types of diabetes require medication to manage blood sugar levels.

Type 1 Diabetes Medications

Individuals with type 1 diabetes must take insulin to regulate their blood sugar levels. Insulin can be administered through injections or an insulin pump. There are several types of insulin available, including rapid-acting, short-acting, intermediate-acting, and long-acting. The type of insulin used will depend on the individual's needs and diabetes management plan.

Rapid-acting insulin begins to work within 15 minutes and lasts for up to four hours. This type of insulin is often used to manage blood sugar levels after meals. Short-acting insulin begins to work within 30 minutes and lasts for up to six hours. This type of insulin is often used to manage blood sugar levels between meals. Intermediate-acting insulin begins to work within two to four hours and lasts for up to 18 hours. Long-acting insulin begins to work within one to two hours and lasts for up to 24 hours.

Type 2 Diabetes Medications

Individuals with type 2 diabetes may not need insulin therapy initially, and may be able to manage their blood sugar levels through lifestyle changes and oral medications. There are several types of oral medications available for type 2 diabetes, including:

  1. Metformin: Metformin is the most common medication for type 2 diabetes. It works by reducing glucose production in the liver and improving insulin sensitivity. It is typically taken once or twice a day with meals.

  2. Sulfonylureas: Sulfonylureas stimulate the pancreas to produce more insulin. They are typically taken once or twice a day before meals. Examples of sulfonylureas include glimepiride, glipizide, and glyburide.

  3. Meglitinides: Meglitinides stimulate the pancreas to produce more insulin, but they have a shorter duration of action than sulfonylureas. They are typically taken before meals. Examples of meglitinides include repaglinide and nateglinide.

  4. Thiazolidinediones: Thiazolidinediones improve insulin sensitivity and reduce glucose production in the liver. They are typically taken once a day. Examples of thiazolidinediones include pioglitazone and rosiglitazone.

  5. DPP-4 inhibitors: DPP-4 inhibitors increase the amount of insulin released by the pancreas and reduce glucose production in the liver. They are typically taken once a day. Examples of DPP-4 inhibitors include sitagliptin, saxagliptin, and linagliptin.

  6. GLP-1 receptor agonists: GLP-1 receptor agonists increase insulin secretion and reduce glucose production in the liver. They also slow down the rate at which food leaves the stomach, which can lead to weight loss. They are typically taken once a day. Examples of GLP-1 receptor agonists include exenatide, liraglutide, and dulaglutide.

  7. SGLT2 inhibitors: SGLT2 inhibitors reduce glucose reabsorption in the kidneys, which increases glucose excretion in the urine.